LOH by regions

• 19q13 LOH
  26 October 2005

  Pathology
  19q13 LOH
  Tumors
  glial tumors oligodendroglioma
  References
  Detection of allelic status of 1p and 19q by microsatellite-based PCR versus FISH: limitations and advantages in application to patient management. Jha P, Sarkar C, Pathak P, Sharma MC, Kale SS, Gupta D, Chosdol K, Suri V. Diagn Mol Pathol. 2011 Mar;20(1):40-7. PMID: #21326038#

• 13q14 LOH
  14 September 2005

  Chromosomal deletion is frequent at the region between BRCA2 and RB1 in the q14 band of chromosome 13 (13q14) in human cancers, including prostate cancer, suggesting the presence of a tumor suppressor gene.
  Tumors
  retinoblastoma
  parathyroid tumors
  Inactivated genes
  RB1
  FOXO1A
  References
  Dong XY, Chen C, Sun X, Guo P, Vessella RL, Wang RX, Chung LW, Zhou W, Dong JT. FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate (...)

• 10q23 LOH
  14 September 2005

  Tumors
  parathyroid tumors
  Driver genes
  PTEN at 10q23
  See also
  Oncobase

• 7q13.3 LOH
  14 September 2005

  Tumors
  parathyroid tumors

• 1q25 LOH
  14 September 2005

  Tumors
  parathyroid tumors

• 1p LOH
  14 September 2005

  Tumors
  parathyroid tumors
  neuroblastomas
  Wilms tumor (#17243164#, #17370329#)
  oligodendroglial tumors
  oligodendrogliomas
  glioblastomas
  Subregions
  1p36 LOH
  neuroblastomas
  1p13 LOH (#17370329#)
  Wilms tumor (#17243164#)
  1p36-pter LOH
  germ cell tumors (#16897744#)
  1p22.3 LOH
  mantle cell lymphoma (#16830336#)
  Candidate genes
  ENO1
  See also
  Oncobase
  References
  Detection of allelic status of 1p and 19q by microsatellite-based PCR versus FISH: limitations and (...)

• 3p25 LOH
  7 July 2005

  Tumors
  clear cell renal cell carcinoma
  serous microcystic pancreatic adenoma (57%) (#14614047#)
  mucinous cystic pancreatic tumors (17%) (#14614047#)
  Candidate genes
  VHL
  OGG1

• 14q LOH
  5 July 2005

  Tumors
  renal cell carcinomas
  neuroblastoma

• 1p34 LOH
  5 July 2005

  1p33-p34 LOH

• 17q23-25 LOH
  4 July 2005

  Tumors
  mammary carcinomas (breast cancer)
  non-serous ovarian carcinomas (64%) (#10723138#)
  other tumors
  Candidate genes
  AXN2

0 | 10 | 20 | 30 | 40 | 50 | 60