D. General pathology

• body
  27 January 2018

  Definition: The body designates the organism in animals. The human body is the human organism.
  See also
  levels of organization / level of organization
  biorganization and organization

• organism
  27 January 2018

  See also
  body human body

• system
  27 January 2018

  systems
  |WKP|
  Definition : A system is a regularly interacting or interdependent group of items forming a unified whole.
  Every system is delineated by its spatial and temporal boundaries, surrounded and influenced by its environment, described by its structure and purpose and expressed in its functioning.
  A system has a function.
  Examples
  biological systems / living systems / biosystems organism / organisms organ systems tissular systems cellular systems molecular (...)

• abetalipoproteinemia
  19 June 2017

  Bassen-Kornzweig syndrome WKP
  Abetalipoproteinemia is a rare autosomal recessive disorder that interferes with the normal absorption of fat and fat-soluble vitamins from food.
  It is caused by a mutation in microsomal triglyceride transfer protein resulting in deficiencies in the apolipoproteins B-48 and B-100, which are used in the synthesis and exportation of chylomicrons and VLDL respectively. It is not to be confused with familial dysbetalipoproteinemia.
  Mutations in the (...)

• systemic functions
  14 June 2017

  Organism functions
  Examples
  predation
  vision
  cognition
  locomotion
  digestion
  energy production respiration
  urinary production
  reproduction sexuality
  See also
  functions / function biological functions

• body plan
  6 March 2017

  WKP
  See also : body / organism / animal
  Definition: A body plan is "an assemblage of morphological features shared among many members of a phylum-level group".
  The vertebrate body plan is one of many: invertebrates consist of many phyla.
  This term, usually applied to animals , envisages a "blueprint" encompassing aspects such as symmetry , segmentation and limb disposition.
  Evolutionary developmental biology seeks to explain the origins of diverse body plans.
  Body plans have (...)

• biological processes
  9 August 2016

  biological process WP
  Definition: Biological processes are the processes vital for a living organism to live.
  Biological processes are made up of many chemical reactions or other events that result in chemical transformation. Metabolism and homeostasis are examples.
  Regulation of biological processes occurs when any process is modulated in its frequency, rate or extent. Biological processes are regulated by many means; examples include the control of gene expression, protein (...)

• viral-human interactome
  12 October 2015

  Open References
  A viral-human interactome based on structural motif-domain interactions captures the human infectome. Segura-Cabrera A, García-Pérez CA, Guo X, Rodríguez-Pérez MA.
  PLoS One. 2013 Aug 8;8(8):e71526. doi:10.1371/journal.pone.0071526 . eCollection 2013. PMID: #23951184# (Free)

• disease module
  10 October 2015

  disease modularity
  See also
  modularity
  References
  A DIseAse MOdule Detection (DIAMOnD) algorithm derived from a systematic analysis of connectivity patterns of disease proteins in the human interactome. Ghiassian SD, Menche J, Barabási AL. PLoS Comput Biol. 2015 Apr 8;11(4):e1004120. doi:10.1371/journal.pcbi.1004120 . eCollection 2015 Apr. PMID: #25853560#
  Disease networks. Uncovering disease-disease relationships through the incomplete interactome. Menche J, Sharma A, Kitsak M, (...)

• epigenetic biomarkers
  5 January 2014

  Epigenetic marks, such as DNA methylation and histone modifications, comprise part of the epigenetic machinery leading to abnormal gene expression and chromatin instability in disease. Epigenetic changes, particularly in human cancers, are now being considered as novel biological markers for diagnostic and therapeutic utility.
  See also
  epigenetics
  biomarkers

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