Therapy, Toxics and drugs

• temsirolimus
  9 December 2007

  Temsirolimus (CCI-779)

• alcoholism
  12 October 2007

  alcohol abuse

• aflatoxin-M1
  1 August 2007

  aflatoxin M1

• BPDE
  18 July 2007

  Benzo[a]pyrene diol epoxide ((+)-7R,8S-dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene) (BPDE) is the carcinogenic product of three enzymatic reactions.
  See also
  benzo[a]pyrene
  BPDE-DNA adducts

• curcuminoids
  18 July 2007

  Types
  curcumin (U1)
  tetrahydrocurcumin (THU1)
  References
  Osawa T. Nephroprotective and hepatoprotective effects of curcuminoids. Adv Exp Med Biol. 2007;595:407-23. PMID: #17569222#

• selective oestrogen-receptor modulators
  8 July 2007

  SORM

• anti-tubulin agents
  8 July 2007

  References
  Jackson JR, Patrick DR, Dar MM, Huang PS. Targeted anti-mitotic therapies: can we improve on tubulin agents? Nat Rev Cancer. 2007 Feb;7(2):107-17. PMID: #17251917#

• anti-mitotic therapies
  8 July 2007

  References
  Jackson JR, Patrick DR, Dar MM, Huang PS. Targeted anti-mitotic therapies: can we improve on tubulin agents? Nat Rev Cancer. 2007 Feb;7(2):107-17. PMID: #17251917#

• phase 0 trials
  8 July 2007

  References
  Kummar S, Kinders R, Rubinstein L, Parchment RE, Murgo AJ, Collins J, Pickeral O, Low J, Steinberg SM, Gutierrez M, Yang S, Helman L, Wiltrout R, Tomaszewski JE, Doroshow JH. Compressing drug development timelines in oncology using phase ’0’ trials. Nat Rev Cancer. 2007 Feb;7(2):131-9. PMID: #17251919#

• rexinoids
  5 July 2007

  References
  Liby KT, Yore MM, Sporn MB. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat Rev Cancer. 2007 May;7(5):357-69. PMID: #17446857#

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