Therapy, Toxics and drugs

• chlorinated methanes
  16 February 2006

  References
  Plaa GL: Chlorinated methanes and liver injury: highlights of the past 50 years. Annu Rev Pharmacol Toxicol 40:42, 2000.

• Toxicity
  16 February 2006

  Toxicology is the scientific discipline that studies the detection, effects, and mechanisms of action of poisons and toxic chemicals. Toxicity is a relative phenomenon that depends on the inherent structure and properties of a chemical and on its dose. Dose-response curves are typically generated in laboratory animals exposed to various amounts of a chemical.
  Despite the inherent limitations of toxicity testing in animals, several important toxicologic principles have been established by (...)

• opioids
  11 February 2006

  References
  Stein C, Schafer M, Machelska H. Attacking pain at its source: new perspectives on opioids. Nat Med. 2003 Aug;9(8):1003-8. PMID: #12894165#

• immunosuppresive drugs
  31 January 2006

  References
  Halloran PF. Immunosuppressive drugs for kidney transplantation. N Engl J Med. 2004 Dec 23;351(26):2715-29. PMID: #15616206#

• beta-lactamases
  31 January 2006

  References
  Jacoby GA, Munoz-Price LS. The new beta-lactamases. N Engl J Med. 2005 Jan 27;352(4):380-91. PMID: #15673804#

• antithyroid drugs
  31 January 2006

  References
  Cooper DS. Antithyroid drugs. N Engl J Med. 2005 Mar 3;352(9):905-17. PMID: #15745981#

• neuraminidase inhibitors
  31 January 2006

  References
  Moscona A. Neuraminidase inhibitors for influenza. N Engl J Med. 2005 Sep 29;353(13):1363-73. PMID: #16192481#

• anticancer agents
  31 January 2006

  References
  Undevia SD, Gomez-Abuin G, Ratain MJ. Pharmacokinetic variability of anticancer agents. Nat Rev Cancer. 2005 Jun;5(6):447-58. PMID: #15928675#

• acetaminophen
  30 January 2006

  Acetaminophen (Tylenol)

• carbon tetrachloride
  30 January 2006

  Carbon tetrachloride (CCl4)

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