Tumoral translocations

• t(X;4)(q22;q31.3)
  2 December 2009

  Tumors
  giant cell reparative granuloma (#10565307#)
  References
  Novel karyotypes in giant cell-rich lesions of bone. Gleason BC, Kleinman PK, Debelenko LV, Rahbar R, Gebhardt MC, Perez-Atayde AR. Am J Surg Pathol. 2007 Jun;31(6):926-32. PMID: #17527082#

• t(12;17)(q15;q23)
  2 December 2009

  Tumors
  extraorbital giant cell angiofibroma (#16527610#)
  References
  A t(12;17) in an extraorbital giant cell angiofibroma. Qian YW, Malliah R, Lee HJ, Das K, Mirani N, Hameed M. Cancer Genet Cytogenet. 2006 Mar;165(2):157-60. PMID: #16527610#

• t(1;2)(p13;q37)
  5 October 2009

  1p13 and 2q37
  Tumors
  giant cell tumor of tendon sheath (#15768862#)
  References
  Giant cell tumor of tendon sheath arising in the toe. Occhipinti E, Heinrich SD, Craver R. Fetal Pediatr Pathol. 2004 Mar-Jun;23(2-3):171-9. PMID: #15768862#

• t(5 ;9)(q33 ;q22)
  26 mars 2009

  Tumors
  peripheral T-cell lymphomas with follicular growth pattern (18%)
  Rare cases of peripheral T-cell lymphomas with follicular growth pattern (PTCL-F) have been reported. Their association with t(5 ;9)(q33 ;q22) involving ITK and SYK has been suggested. This rare form of PTCL has an immunophenotype indicative of derivation from TFH cells. It is associated with t(5 ;9) in a proportion of cases. It shows some overlapping features with angioimmunoblastic T-cell lymphoma, raising the (...)

• t(1;13)(p36;q14)
  21 October 2008

  Tumors
  alveolar rhabdomyosarcoma (ARMS) (15%)
  Molecular biology
  PAX7-FOXOA1 (PAX7-FKHR)

• t(16;21)(q24;q22)
  29 September 2008

  Tumor
  acute myeloblastic leukemia (#18656694#)
  Molecular biology
  RUNX1-MTG16 fusion gene (#18656694#)
  NB: The significant homology between MGT16 and MTG8 suggests that the RUNX1-MTG16 fusion gene induced by the t(16;21)(q24;q22) is a variant of the RUNX1-MTG8 that shares similar activity.
  References
  De Braekeleer E, Douet-Guilbert N, Le Bris MJ, Morel F, Férec C, De Braekeleer M. RUNX1-MTG16 fusion gene in acute myeloblastic leukemia with t(16;21)(q24;q22): case report and review of (...)

• t(2;7)(p11.2;q22)
  19 May 2008

  Tumors
  low-grade B-cell lymphoma (#18262057#)
  References
  Ambika S, Oo TH. Translocation (2;7)(p11.2;q22) in a newly diagnosed low-grade B-cell non-Hodgkin lymphoma. Cancer Genet Cytogenet. 2008 Feb;181(1):65-6. PMID: #18262057#

• t(3;9)(p14;q34)
  19 May 2008

  Tumors
  chronic myeloid leukemia (CML) (#18262060#)
  References
  Bennour A, Sennana H, Laatiri MA, Khelif A, Saad A. A masked BCR/ABL rearrangement in a case of chronic myeloid leukemia with translocation t(3;9)(p14;q34). Cancer Genet Cytogenet. 2008 Feb;181(1):72-4. PMID: #18262060#

• t(19;22)(q13.2;q12.2)
  19 May 2008

  Tumors
  Ewing sarcoma (#18295659#)
  References
  Maire G, Brown CW, Bayani J, Pereira C, Gravel DH, Bell JC, Zielenska M, Squire JA. Complex rearrangement of chromosomes 19, 21, and 22 in Ewing sarcoma involving a novel reciprocal inversion-insertion mechanism of EWS-ERG fusion gene formation: a case analysis and literature review. Cancer Genet Cytogenet. 2008 Mar;181(2):81-92. PMID: (...)

• t(8;9)(p11;q33)
  19 May 2008

  Translocation t(8;9)(p11;q33) joining CEP110 (9q33) to FGFR1 (8p11.2-p11.1).
  Tumors
  precursor T-cell lymphoma with hypereosinophilic syndrome in 8p11 myeloproliferative syndrome (EMS)
  References
  Park TS, Song J, Kim JS, Yang WI, Song S, Kim SJ, Suh B, Choi JR. 8p11 myeloproliferative syndrome preceded by t(8;9)(p11;q33), CEP110/FGFR1 fusion transcript: morphologic, molecular, and cytogenetic characterization of myeloid neoplasms associated with eosinophilia and FGFR1 abnormality. (...)

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