Pancreas

• pancreatic serous cystadenoma
  19 December 2012

  pancreatic SCA
  Synopsis : Microcystic serous cystadenomas
  10% of resected pancreatic cystic lesions
  central scar
  excellent prognosis.
  Digital case
  JRC:14765: Microcystic (serous) pancreatic cystadenoma (plus insular pabcreas).
  Images
  Macroscopy https://twitter.com/smlungpathguy/status/741026018102632448 https://twitter.com/E_Heidi_Cheek/status/870447703955787778
  Serous cystadenoma of the pancreas https://twitter.com/Konzult_/status/741181159678349312 (...)

• solid pseudopapillary tumor of the pancreas with multinucleated giant tumor cells
  17 December 2012

  Solid pseudopapillary neoplasm of the pancreas with prominent atypical multinucleated giant tumour cells
  Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low-grade malignant neoplasm. SPN with prominent atypical multinucleated giant tumour cells (MNGTCs) has been very rarely reported.
  The presence of MNGTCs in SPN most probably represents degenerative change of the tumour cells and does not seem to affect the prognosis.
  Reference
  Solid pseudopapillary neoplasm of the (...)

• undifferentiated carcinoma with osteoclastic giant cells
  29 November 2012

  UCOCGC; poorly differentiated carcinoma with osteoclastic giant cells
  Images
  Poorly differentiated carcinoma with osteoclast-like giant cells of pan.tail https://twitter.com/sam_albadri/status/789066049840754688
  Cytology of UCOCGC https://twitter.com/CancerCytopath/status/848930936108576768
  See also
  pancreatic carcinomas
  Paywall Reference
  Undifferentiated carcinoma with osteoclastic giant cells (UCOCGC) of the pancreas associated with the familial atypical multiple mole (...)

• sporadic well-differentiated pancreatic neuroendocrine tumor
  2 July 2012

  sporadic well-differentiated pancreatic neuroendocrine tumors
  Molecular biology
  ATRX / DAXX Approximately 45% of sporadic well-differentiated pancreatic neuroendocrine tumors harbor mutations in either ATRX (alpha thalassemia/mental retardation X-linked) or DAXX (death domain-associated protein). These novel tumor suppressor genes encode nuclear proteins that interact with one another and function in chromatin remodeling at telomeric and peri-centromeric regions. Mutations in these (...)

• MEN1-associated pancreatic neuroendocrine tumor
  2 July 2012

  MEN-1 syndrome pancreatic neuroendocrine tumors
  Pathology
  Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. (#22575867#)
  References
  Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. de (...)

• pancreatic neuroendocrine tumors
  19 April 2012

  pancreatic neuroendocrine tumor; pancreatic neuroendocrine tumors; PanNETs, PanNET
  Images
  neuroendocrine tumour of pancreas
  https://twitter.com/Tenonhospital/status/816668255389700096
  Digital cases
  JRC:18768 : Pancreatic neuroendocrine tumor (Pancreas carcinoid-islet tumors)
  Grading
  Accurate grading w/Ki-67 index on FNA specimens using the WHO 2010/ENETS criteria.
  See also
  pancreatic neuroendocrine neoplasma (PanNENs )
  neuroendocrine tumors
  pancreatic tumors
  Open (...)

• pancreatic solid and pseudopapillary tumor with neuroendocrine differentiation
  16 April 2012

  Pancreas solid and pseudopapillary tumor with neuroendocrine differentiation
  Digital case
  JRC:14615 : Pancreas solid and pseudopapillary tumor (with neuroendocrine differentiation)
  See also
  pancreatic solid and pseudopapillary tumor

• VIPoma
  11 April 2012

  vasointestinal peptide secreting
  Digital case
  JRC:476 : Islet cell tumor (VIPoma)
  See also
  islet cell tumor

• glucagonoma
  11 April 2012

  Digital case
  JRC:475 : Islet cell tumor (glucagonoma)
  See also
  insular tumors (islet cell tumor)

• tuberous sclerosis-associated pancreatic neuroendocrine carcinoma
  26 March 2012

  pancreatic neuroendocrine carcinoma in tuberous sclerosis
  References
  Well-differentiated pancreatic neuroendocrine carcinoma in tuberous sclerosis—case report and review of the literature. Arva NC, Pappas JG, Bhatla T, Raetz EA, Macari M, Ginsburg HB, Hajdu CH. Am J Surg Pathol. 2012 Jan;36(1):149-53. PMID: #22173120#

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