Macroscopical synopsis

 thin marfanoid build
 facial asymmetry
 downward-slanting palpebral fissures
 depressed nasal bridge
 small nose with bulbous tip
 mild mental retardation

References

 Ehling D, Kennerknecht I, Junge A, Prager B, Exeler R, Behre B, Horst J, Schmitt-John T, Bartsch O, Wirth J. Mild phenotype in two unrelated patients with a partial deletion of 21q22.2-q22.3 defined by FISH and molecular studies. Am J Med Genet. 2004 Dec 15;131A(3):265-72. PMID: 15534873