meningiomas

Subtypes

- angiomatous meningioma (meningiomas whose vascular component exceeded 50% of the total tumor) (15104303)
- aggressive meningioma
- undifferentiated meningeal sarcoma
- clear cell meningioma

LOH

- 1p LOH
- 9q LOH
- 10q LOH
- 14q LOH
- 22q LOH

Gene mutations

- somatic mutations or deletions of NF2

References

- Perry A, Gutmann DH, Reifenberger G. Molecular pathogenesis of meningiomas. J Neurooncol. 2004 Nov;70(2):183-202. PMID: 15674477

- Lamszus K, Kluwe L, Matschke J, Meissner H, Laas R, Westphal M. Allelic losses at 1p, 9q, 10q, 14q, and 22q in the progression of aggressive meningiomas and undifferentiated meningeal sarcomas. Cancer Genet Cytogenet. 1999 Apr 15;110(2):103-10. PMID: 10214357

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