In approximately 20 to 30% of patients with systemic mastocytosis (SM), an associated clonal hematological nonmast cell lineage disorder (AHNMD) is diagnosed. SM may be considered to be closely related to the myeloproliferative disorders (MPDs).
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References
Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast cell lineage disorder carrying the activating point mutations KITD816V and JAK2V617F. Sotlar K, Bache A, Stellmacher F, Bültmann B, Valent P, Horny HP. J Mol Diagn. 2008 Jan;10(1):58-66. PMID: 18165278