genetic instability; genome instability
Definition: Genomic instability is considered as a significant factor in the pathogenesis of cancer.
There are several patterns of genomic instability, which are reflections of different functional defects in the cancer cells.
Genomic instability can be divided into 2 categories: Retour ligne manuel
chromosomal instability (CIN) Retour ligne manuel
microsatellite instability (MSI).
Genetic alterations can affect the structure of chromosomes, (...)
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