References
Systematic structure-function analysis of androgen receptor L701 mutants explains the properties of the prostate cancer mutant L701H. van de Wijngaart DJ, Molier M, Lusher SJ, Hersmus R, Jenster G, Trapman J, Dubbink HJ. J Biol Chem. PMID: #20007693#
Home > Keywords > Proteins > Mutant protein
Mutant protein
Articles
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AR-701H
5 January 2010 -
BRAF-V600E
2 February 2010BRAF is an oncogene that is commonly mutated in both melanomas and papillary thyroid carcinomas (PTCs).
Usually, mutations in the codons 600 or 601 lead to constitutive activity in the Ras-mitogen-activated protein kinase pathway.
Neoplasms associated with BRAF-V600E mutations:
histiocytic proliferations
Langerhans cell histiocytosis
Erdheim-Chester disease
juvenile xanthogranuloma family neoplasms (#31685033#)
-* BRAF V600E mutations are not an oncogenic driver of solitary (...) -
KIT-D816V
29 November 2011KIT(D816V)
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AKT1-pS473
14 January 2011AKT-pS473
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APOC3
23 June 2010APOLIPOPROTEIN C-III; APOC3; APO C III