Disease

Articles

• celiac disease
  6 April 2004

  coeliac disease; celiac sprue; gluten-sensitive enteropathy
  Definition: Celiac disease is a common autoimmune condition triggered by ingesting one of several related proteins found in wheat, barley, and rye: the gliadins, hordeins, and secalins.
  In susceptible persons, ingestion of these proteins leads to infiltration of the intestinal mucosa by both intraepithelial CD8+ lymphocytes and CD4+ lamina propria lymphocytes and, ultimately, to crypt hyperplasia and villous atrophy.
  Symptoms (...)

• sarcoidosis
  22 September 2003

  Sarcoidosis is a granulomatous disorder of unknown etiology, associated with an accumulation of CD4+ T cells and a TH1 immune response. WP
  Images
  hepatic sarcoidosis https://twitter.com/Hopkins_GI_Path/status/675402892036173826
  cutaneous sarcoidosis https://twitter.com/RyanHickMD/status/731249607909351424
  Sarcoidosis: all types of giant cells and endogenous inclusions occur, none are specific https://twitter.com/smlungpathguy/status/879435684540538884
  Links
  Sarcoidosis in (...)

• obesity
  19 April 2004

  Obesity is associated with many adverse health effects, including an increased risk of diabetes and heart disease.
  The combined condition of obesity, diabetes and heart disease is sometimes referred to as the metabolic syndrome.
  One of the factors that best correlates obesity with the rest of the metabolic syndrome is not overall body mass, but the distribution of adipose tissue in the abdominal region, visceral obesity.
  Obesity is a global epidemic resulting from sedentary lifestyles, (...)

• cryptococcosis
  14 March 2007

  cryptococcal infections, cryptococcoses

• arterial hypertension
  16 January 2006

  Hypertension is a common health problem with some-times devastating consequences, and often remains asymptomatic until late in its course. Hypertension is one of the most important risk factors for both coronary artery disease and cerebrovascular accidents; hypertension can lead to cardiac hypertrophy and, potentially, heart failure, aortic dissection, and renal failure.
  It is widely acknowledged that hypertension is a complex, multifactorial disease that has both genetic and environmental (...)

• staphylococcal scalded skin syndrome
  5 February 2006

  SSSS, Ritter disease

• ataxia telangiectasia
  27 October 2003

  Definition: Ataxia telangiectasia (AT) is another autosomal recessive disorder characterized by cerebellar ataxia, progressive mental retardation, immune defects, severe muscular incoordination, and a strong predisposition to malignancy, particularly in the lymphoreticular system. The term telangiectasia describes the dilatation of blood vessels, particularly in the eyes and skin.
  Patients with this disease have several defects, including hypersensitivity to ionising radiation. Death is (...)

• CDPX2
  14 January 2005

  X-linked dominant chondrodysplasia punctata type 2

• del(21)(q22) syndrome
  30 October 2010

  21q22 deletion syndrome

• renal allograft rejection
  15 March 2004

  renal transplant rejection
  Digital case
  UI:774 : acute renal allograft rejection
  Types
  acute renal allograft rejection
  chronic renal allograft rejection
  Links
  Transplant Pathology at the Univ. of Pittsburgh
  References
  Cornell LD, Smith RN, Colvin RB. Kidney transplantation: mechanisms of rejection and acceptance. Annu Rev Pathol. 2008;3:189-220. PMID: #18039144#

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