Disease

Articles

• obesity
  19 April 2004

  Obesity is associated with many adverse health effects, including an increased risk of diabetes and heart disease.
  The combined condition of obesity, diabetes and heart disease is sometimes referred to as the metabolic syndrome.
  One of the factors that best correlates obesity with the rest of the metabolic syndrome is not overall body mass, but the distribution of adipose tissue in the abdominal region, visceral obesity.
  Obesity is a global epidemic resulting from sedentary lifestyles, (...)

• Gardner syndrome
  9 August 2004

  Images
  focal matrical focus in epidermoid cyst : a clue to Gardner’s syndrome
  https://twitter.com/BenjaminAwood/status/817171629843316736
  https://www.ncbi.nlm.nih.gov/pubmed/27914683
  Synopsis
  digestive tumors predisposition
  numerous adenomatous colonic polyps (colonic adenomas)
  gastric fundic gland polyposis
  duodenal ampulloma
  adenoma of the common human bile duct (#9250908#)
  jejunal myoepithelial hamartoma
  minor dental abnormalities
  caniofacial osteomas
  mandibular (...)

• Hirschsprung disease
  6 October 2003

  Hirschsprung’s disease, congenital intestinal aganglionosis, digestive aganglionnosis; digestive aganglionoses PO1 PO2
  Definition: Aganglionic megacolon is associated with congenital absence of intrinsic ganglion cells in the myenteric (Auerbach) and submucosal (Meissner) plexuses of the gastrointestinal tract. The disorder is genetically heterogeneous.
  Digital cases
  HPC:90 : rectal mucosa biopsies
  HPC:98 : rectal mucosa biopsies
  HPC:151 : Hirschsprung disease - Rectal (...)

• familial adenomatous polyposis
  20 November 2003

  adenomatous polyposis, FAP

• asthma
  12 November 2003

  Definition: Asthma is a chronic respiratory condition that affects children and adults. Genetic predisposition and environmental factors interact to produce the disease.
  Images
  Asthma; airway parietal edema , smooth muscle hyperplasia , mucus gland hyperplasia
  https://twitter.com/H_Elshoni/status/747268830955593729
  Types
  acute asthma
  chronic asthma
  Synopsis
  mucus plugs
  mucosal eosinophilic infiltrate
  mucosal basement membrane thickening with sunmembranous collagen (...)

• trichotillomania
  16 June 2004

  ETIOLOGY: abnormal compulsion to pull out hail
  HISTOPATHOLOGY: marker increase in catagen and telogen hairs, possible follicular damage, pigmented casts, possible trichomalacia, and inflammatory changes usually absent
  OTHER CAUSES OF PATCHY ALOPECIA: alopecia areata, tinea capitis, loose anagen syndrome, traction and pressure alopecia, secondary syphilis, tick bite alopecia, aplasia cutis, congenital triangular alopecia, familial focal alopecia, (...)

• Niemann-Pick disease type B
  15 August 2012

  NPDB; acid sphingomyelinase deficiency
  Definition: NPD type B is a rare inborn error of metabolism of autosomal recessive inheritance. Patients with Niemann-Pick disease type B (NPDB) have a benign course and prognosis. It is mainly a visceral form without neurologic manifestations despite the massive visceral involvement. NPDB is caused by mutations in the acid lysosomal sphingomyelin phosphodiesterase-1 gene (SMPD1) (MIM.607608)
  Digital slides
  Case 52 (HPC:52) : Liver in (...)

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