Cancer gene

Articles

• FAM123B
  18 June 2007

  WTX, family with sequence similarity 123, member 123

• TFPT
  26 June 2007

  TCF3 fusion partner

• MALAT1
  26 June 2007

  metastasis-associated lung adenocarcinoma transcript 1

• BCOR
  1 January 2011

  BCL6 corepressor; FLJ20285, KIAA1575
  The BCOR-CCNB3 fusion gene, resulting from a chromosome X paracentric inversion, was described in translocation-negative ’Ewing-like’ sarcomas arising in bone and soft tissue.
  Pathology
  BCOR-CCNB3 gene fusion in Ewing-like sarcoma . (#22387997#)
  CCNB3 immunohistochemistry is a powerful diagnostic marker for this subgroup of sarcoma and that overexpression of BCOR-CCNB3 or of truncated CCNB3 activates S phase in NIH3T3 cells.
  The intrachromosomal (...)

• MGEA5
  13 January 2017

  |WKP|
  Definition: Bifunctional protein NCOAT is a protein that in humans is encoded by the MGEA5 gene.
  Pathology
  Consistent t(1;10) with rearrangements of TGFBR3 and MGEA5 in : myxoinflammatory fibroblastic sarcoma (#21717526#) hemosiderotic fibrolipomatous tumor (#21717526#) PHAT pleomorphic hyalinizing angiectatic tumor
  Open References
  Consistent t(1;10) with rearrangements of TGFBR3 and MGEA5 in both myxoinflammatory fibroblastic sarcoma and hemosiderotic fibrolipomatous (...)

• PDGFRA
  12 December 2003

  platelet-derived growth factor receptor (PDGFR) alpha, PDGFR-alpha

• ZNF384
  18 June 2007

  CIZ, NMP4

• EML4
  23 July 2007

  Pathology
  EML4-ALK fusion gene in non-small-cell lung cancer (6.7% of NSCLC) (#17625570#)
  See also
  EMLs: EML1, EMl2, EML3
  References
  Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara SI, Watanabe H, Kurashina K, Hatanaka H, Bando M, Ohno S, Ishikawa Y, Aburatani H, Niki T, Sohara Y, Sugiyama Y, Mano H. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature. 2007 Jul 11; PMID: #17625570#
  Heidebrecht, H. J.; Buck, F.; (...)

• PVRL2
  29 August 2007

  Function
  Entry of the poliovirus into permissive cells is dependent on the expression of a specific receptor, the poliovirus receptor (PVR; 173850), which is an integral membrane glycoprotein.
  Its extracellular region exhibits 3 immunoglobulin-like domains. Two integral forms, PVR-alpha and PVR-delta, and 2 soluble forms, PVR-beta and PVR-gamma, are lacking a transmembrane region generated by alternative splicing of mRNA. The normal cellular function of PVR is unknown.
  Pathology (...)

• ATF2
  29 August 2007

  CREB2, CREBP1

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