Microsatellites are unique highly polymorphic and informative genetic markers dispersed in the human genome.
Use in tumors
Microsatellites have become the most commonly used markers to trace loss of heterozygosity in tumors. Their detection by PCR is rapid and can be semi-automated with maximal robustness and reproducibility.
References
Ellegren H. Microsatellites: simple sequences with complex evolution. Nat Rev Genet. 2004 Jun;5(6):435-45. PMID: #15153996#
Jin L, Baskett ML, (...)
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Molecular structure
Articles
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microsatellites
28 May 2004 -
NADH
2 June 2004WKP
Definition: Nicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. The compound is a dinucleotide, because it consists of two nucleotides joined through their phosphate groups. One nucleotide contains an adenine base and the other nicotinamide. Nicotinamide adenine dinucleotide exists in two forms, an oxidized and reduced form abbreviated as NAD+ and NADH respectively.
See also : NADPH
Functions
In metabolism, nicotinamide adenine dinucleotide is involved (...) -
peptide bond
7 March 2004peptidic bond
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promoter
18 August 2004Features
promoter swapping -
molecular anatomy
20 April 2004Features
intercellular junctions
local adhesion complex
sarcomere