Home > E. Pathology by systems > Nervous system > Central nervous system > Brain > bipolar disorder
bipolar disorder
Monday 29 September 2003
Susceptibility loci
ch. 1 (15208783)
locus 2q22-q24 (17924339)
ch. 3 (15208783)
6q22 (15060841, 16103985)
locus 6q23-q24 (17924339)
8q (16103985)
ch. 11 (15208783)
13q33 (17924339)
18q22 (15208783)
22q (17924339)
Epistatic effects between loci on chromosomes 2q and 6q (17924339)
Reviews
Sundram S, Joyce PR, Kennedy MA. Schizophrenia and bipolar affective disorder: perspectives for the development of therapeutics. Curr Mol Med. 2003 Aug;3(5):393-407. PMID: 12942993
Harwood AJ. Neurodevelopment and mood stabilizers. Curr Mol Med. 2003 Aug;3(5):472-82. PMID: 12943000
Castren E. Is mood chemistry? Nat Rev Neurosci. 2005 Mar;6(3):241-6. PMID: 15738959
Avissar S, Schreiber G. Toward molecular diagnostics of mood disorders in psychiatry. Trends Mol Med. 2002 Jun;8(6):294-300. PMID: 12067616
References
Abou Jamra R, Fuerst R, Kaneva R, Orozco Diaz G, Rivas F, Mayoral F, Gay E, Sans S, Gonzalez MJ, Gil S, Cabaleiro F, Del Rio F, Perez F, Haro J, Auburger G, Milanova V, Kostov C, Chorbov V, Stoyanova V, Nikolova-Hill A, Onchev G, Kremensky I, Jablensky A, Schulze TG, Propping P, Rietschel M, Nothen MM, Cichon S, Wienker TF, Schumacher J. The First Genomewide Interaction and Locus-Heterogeneity Linkage Scan in Bipolar Affective Disorder: Strong Evidence of Epistatic Effects between Loci on Chromosomes 2q and 6q. Am J Hum Genet. 2007 Nov;81(5):974-86. PMID: 17924339
