Home > E. Pathology by systems > Reproductive system > Leydig cell tumor
Leydig cell tumor
Monday 13 February 2006
Leydig cell adenoma
Digital cases
HPC:119 : Leydig cell tumor.
JRC:18782 : Testis intestitial cell tumor
Images
Leydig cell tumor
- https://twitter.com/MayoClinicPath/status/743120235230699520
- https://twitter.com/seattlequinns/status/857024877034848256
Reinke crystals in a Leydig cell tumour
Synopsis
Leydig cell proliferation
- round cell proliferation
- fusiform cell proliferation
- abundant eosinophilic cytoplasm
- characteristic nuclear-rich zones separated by nuclear-free zones
- crystals of Reinke (Reinke crystals)
Localization
ovarian Leydig cell tumor
testicular Leydig cell tumor (Leydig cell tumor of the testis)
- paratesticular Leydig cell tumor
Variants
microcystic Leydig cell tumor (10328086)
Differential diagnosis
See also
Sertoli-stromal cell tumors
- Sertoli cell tumor (SCT)
- large cell calcifying Sertoli cell tumor (LCCSCT)
- Sertoli-Leydig cell tumor
- Leydig cell tumor (Leydig cell adenoma)
- Leydig cell hyperplasia
References
Billings SD, Roth LM, Ulbright TM. Microcystic Leydig cell tumors mimicking yolk sac tumor: a report of four cases. Am J Surg Pathol. 1999 May;23(5):546-51. PMID: 10328086
Leydig cell tumor of the testis: a clinicopathologic, DNA content, and MIB-1 comparison of nonmetastasizing and metastasizing tumors. Cheville JC, Sebo TJ, Lager DJ, Bostwick DG, Farrow GM. Am J Surg Pathol. 1998 Nov;22(11):1361-7. PMID: 9808128
