PRKCs
Protein kinase C is a key enzyme of intracellular signal transduction. Protein kinase C (PKC) is the major phorbol ester receptor.
The genes encoding the protein kinase C enzymes are widely distributed, e.g., PRKCA (MIM.176960) on chromosome 17, PRKCB1 (MIM.176970) on 16, and PRKCG (MIM.176980) on 19.
Although the sequence homology among the PRKC family of genes is extensive, the pattern of expression varies among tissues. For example, the delta polypeptide PRKCD appears to be the major isoform expressed in mouse hematopoietic cells.
Memebers
| PRKCA | PRKCB1 | PRKCG | PRKCD |