Home > E. Pathology by systems > Locomotory system > Bones > fibular hypoplasia
fibular hypoplasia
Monday 23 January 2006
Congenital aplasia or hypoplasia of the fibula (FAH) is a rare malformation that is defined by a partial or complete absence of the fibular bone.
Etiology and pathogenesis are unknown and the precise morphology of the tissue cord replacing the malformed fibula has not been well described.
Etiology (Examples)
otopalatodigital syndrome type 2 (OPD2)
Types
unilateral hypoplastic fibula
bilateral hypoplastic fibulae
- symmetric hypoplastic fibulae
- asymmetric hypoplastic fibulae
Individual associations
oligodactyly
ectrodactyly
Familial associations
proximal focal femoral deficiency (PFFD)
See also
lateral ray defects
fibular developmental field
References
Hermanns-Sachweh B, Stemper A, Klosterhalfen B, Senderek J, Buttner R, Weber M. Light microscopic, immunohistochemical, and ultrastructural findings in congenital fibular aplasia or hypoplasia (FAH). Pediatr Dev Pathol. 2005 Jul-Aug;8(4):474-82. PMID: 16211453
