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Marburg

Monday 2 January 2006

Ebola and Marburg viruses, family Filoviridae, are among the best known examples of emerging and re-emerging pathogens.

Although outbreaks have been sporadic and geographically restricted to areas of Central Africa, the hemorrhagic fevers caused by these viruses are remarkably severe and are associated with high case fatality rates often exceeding 80 percent.

In addition to humans, these viruses have decimated populations of wild apes in Central Africa.

Currently, there are no vaccines or effective therapies available for human use.

References

- Hensley LE, Jones SM, Feldmann H, Jahrling PB, Geisbert TW. Ebola and Marburg viruses: pathogenesis and development of countermeasures. Curr Mol Med. 2005 Dec;5(8):761-72. PMID: 16375711