chronic disseminated candidiasis

Definition: Chronic disseminated candidiasis (CDC or hepatosplenic candidiasis) is a form of invasive fungal infection that occurs most commonly in patients with acute leukemia treated with chemotherapy.

Types

 hepatosplenic candidiasis

Predisposition

 chemotherapy for acute leukemias

See also

 Infections

• fungal infections
  • Candida sp. (Candida albicans)
  • Candidiases
    • systemic candidiasis (disseminated Candida infection)

References

 Granulocyte colony stimulating factor-induced exacerbation of fungus-related immune restoration inflammatory syndrome: a case of chronic disseminated candidiasis exacerbation. Chandesris MO, Kelaidi C, Méchaï F, Bougnoux ME, Brousse N, Viard JP, Poirée S, Lecuit M, Hermine O, Lortholary O. J Microbiol Immunol Infect. 2010 Aug;43(4):339-43. PMID: 20688295

 Masood A, Sallah S. Chronic disseminated candidiasis in patients with acute leukemia: emphasis on diagnostic definition and treatment. Leuk Res. 2005 May;29(5):493-501. PMID: 15755501

 Kontoyiannis DP, Luna MA, Samuels BI, Bodey GP. Hepatosplenic candidiasis. A manifestation of chronic disseminated candidiasis. Infect Dis Clin North Am. 2000 Sep;14(3):721-39. PMID: 10987117