Humpath.com - Human pathology

Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Liver > adenoviral ascending cholangiohepatitis

adenoviral ascending cholangiohepatitis

Thursday 8 December 2005

Definition: Ascending infection from the gastrointestinal tract to the biliary tree. Adenoviral cholangiohepatitis occurs as a result of ascending infection by Adenovirus from the gastrointestinal tract to the biliary tree.

Predisposition

- acquired immunodeficiencies

  • allograft (liver transplantation)
  • acquired human immunodeficiency virus (HIV) infection (AIDS)

Synopsis

- slight hepatocytic necrosis
- cholangiohepatitis
- progressive loss of interlobular bile ducts
- adenoviral infection of the biliary tree
- necrotizing cholangitis
- adenoviral inclusions in the biliary epithelium

See also

- adenovirus
- adenoviral infections

  • adenovirus gastrointestinal infection
  • adenoviral cholangitis

References

- Brundler MA, Rodriguez-Baez N, Jaffe R, Weinberg AG, Rogers BB. Adenovirus ascending cholangiohepatitis. Pediatr Dev Pathol. 2003 Mar-Apr;6(2):156-9. PMID: 12574911