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defective iodide transport diseases

Synopsis

- large congenital goiter (up to 150 g).
- hypothyroidism
- atypical cells
- hyperplastic pattern with predominant microfollicular aspect

Electron microscopy

- hyperactive follicular cell with folding of the basal membrane

See also

- NIS symporter protein mutations

References

- Camargo RY, Gross JL, Silveiro SP, Knobel M, Medeiros-Neto G. Pathological Findings in Dyshormonogenetic Goiter with Defective Iodide Transport. Endocr Pathol. 1998 Autumn;9(3):225-233. PMID: #12114713#