Definition: Guanine is a purine base (nitrogenous base) and constituent of nucleotides and as such one member of the base pair G-C (guanine and cytosine).
Guanine is one of the five main nucleobases found in nucleic acids (e.g., DNA and RNA). Guanine is a purine derivative, and in Watson-Crick base pairing forms three hydrogen bonds with cytosine. Guanine "stacks" vertically with the other nucleobases via aromatic interactions. Guanine is a tautomer (see keto-enol tautomerism). The guanine nucleoside is called guanosine.
See also