natural IgM
Natural IgM antibodies play an important role in immunosurveillance mechanisms against transformed cells.
References
Vollmers HP, Brandlein S. The "early birds": natural IgM antibodies and immune surveillance. Histol Histopathol. 2005 Jul;20(3):927-37. PMID: #15944943#
Vollmers HP, Brandlein S. Death by stress: natural IgM-induced apoptosis. Methods Find Exp Clin Pharmacol. 2005 Apr;27(3):185-91. PMID: #15834451#
Brandlein S, Vollmers HP. Natural IgM antibodies, the ignored weapons in tumour immunity. Histol Histopathol. 2004 Jul;19(3):897-905. PMID: #15168352#
Brandlein S, Pohle T, Ruoff N, Wozniak E, Muller-Hermelink HK, Vollmers HP. Natural IgM antibodies and immunosurveillance mechanisms against epithelial cancer cells in humans. Cancer Res. 2003 Nov 15;63(22):7995-8005. PMID: #14633732#
Vollmers HP, Brandlein S. Nature’s best weapons to fight cancer. Revival of human monoclonal IgM antibodies. Hum Antibodies. 2002;11(4):131-42. PMID: #12775893#