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SDCs
Saturday 19 July 2003
The syndecans (SDCs) mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein.
Members
syndecan-1 (SDC1) (MIM.186355) (CD138)
syndecan-2 (SDC2) (MIM.142460) (fibroglycan, heparan sulfate proteoglycan)
syndecan-3 (SDC3) (MIM.186357) (N-syndecan)
syndecan-4 (SDC4) (MIM.600017) (ryudocan, amphiglycan)
References
Morgan MR, Humphries MJ, Bass MD. Synergistic control of cell adhesion by integrins and syndecans. Nat Rev Mol Cell Biol. 2007 Dec;8(12):957-69. PMID: 17971838
