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replication fork

Sunday 12 June 2005

Definition: Replication fork is the region of replicating DNA in which active DNA synthesis is occurring to generate two copies of the parental DNA.

References

- Heller RC, Marians KJ. Replisome assembly and the direct restart of stalled replication forks. Nat Rev Mol Cell Biol. 2006 Dec;7(12):932-43. PMID: 17139333

- Cleary JD, Pearson CE. Replication fork dynamics and dynamic mutations: the fork-shift model of repeat instability. Trends Genet. 2005 May;21(5):272-80. PMID: 15851063