Home > A. Molecular pathology > POLB
POLB
MIM.174760 8p11.2
Friday 27 May 2005
In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA maintenance, replication, recombination, and drug resistance.
Two important enzymatic steps in mammalian BER are contributed by POLB: DNA resynthesis of the repair patch and lyase removal of the 5-prime-deoxyribose phosphate.
Pathology
base excision repair (BER)
