urethral obstruction sequence

Synopsis

 megacystis

• prune belly sequence

 bilateral megaureteres
 bilateral hydronephrosis
 bilateral ostructive renal dysplasia
 oligohydramnios sequence

Case records

 Case record #10038
 Case record #11598: Megacystis in urethral obstruction sequence (UOS) with prune belly syndrome

References

 Berry C. Patterns of congenital lower urinary tract obstructive uropathy.
Pediatr Dev Pathol. 2003 Mar-Apr;6(2):202-3; author reply 203. PMID: 12574913

 Volmar KE, Fritsch MK, Perlman EJ, Hutchins GM. Patterns of congenital lower urinary tract obstructive uropathy: relation to abnormal prostate and bladder development and the prune belly syndrome. Pediatr Dev Pathol. 2001 Sep-Oct;4(5):467-72. PMID: 11779049

 Poucell-Hatton S, Huang M, Bannykh S, Benirschke K, Masliah E. Fetal obstructive uropathy: patterns of renal pathology. Pediatr Dev Pathol. 2000 May-Jun;3(3):223-31. PMID: 10742409

 Fryns JP, Vandenberghe K, Deschrijver D. Early urethral obstruction sequence and unbalanced translocation with terminal 10p duplication/1p deficiency. Genet Couns. 1997;8(4):349-50. PMID: 9457507

 van Buggenhout G, Cooreman G, Thienpont L, Fryns JP. Early urethral obstruction sequence and trisomy of the long arm of chromosome 1. Ann Genet. 1995;38(2):106-7. PMID: 7486825

 Bierkens AF, Feitz WF, Nijhuis JG, de Wildt MJ, Flos MS, de Vries JD. Early urethral obstruction sequence: a lethal entity? Fetal Diagn Ther. 1996 Mar-Apr;11(2):137-45. PMID: 8838771

 Perez-Aytes A, Graham JM, Hersh JH, Hoyme HE, Aleck K, Carey JC. Urethral obstruction sequence and lower limb deficiency: evidence for the vascular disruption hypothesis. J Pediatr. 1993 Sep;123(3):398-405. PMID: 8355115