ganglioneuroblastomas
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Digital cases
Case 26 : nodular ganglioneuroblastoma
Definition : The ganglioneuroblastoma are rare lesions with widespread neuronal differentiation that have been classified as intermediate stages between neuroblastoma and ganglioneuroma.
Types
intermixed ganglioneuroblastoma
nodular ganglioneuroblastoma
Cytogenetics
constitutional t(1;13)(q21;q12) with truncation and inactivation of WASF3 (#7972239#)
CGH
Losses
Gains
- 2p25-pter (60%)
- 5p15.1-p15.3 (60%)
- 7 (60%)
- 13q22-q31 (60%)
- 22 (60%)
See also
neuroblastic tumors
- neuroblastomas
References
Joshi VV. Peripheral neuroblastic tumors: pathologic classification based on recommendations of international neuroblastoma pathology committee (Modification of shimada classification). Pediatr Dev Pathol. 2000 Mar-Apr;3(2):184-99. PMID: #10679039#