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hepatic epitheiloid hemangioendothelioma

Monday 24 January 2005

liver EHE; hepatic EHE ; EHAE

Definition : Epithelioid hemangioendothelioma is best considered a vascular neoplasm of intermediate malignancy. Although usually progressive, the clinical course is highly unpredictable.

Images

- hepatic EHE

Cases

- http://www.uab.edu/medicine/pathology/152-education/unknown-cases/245-unknowncases-case22-april2017

Association

- hepatic allograft (9060595)

Immunochemistry

- CD34+
- FVIII+ (Factor VIII)
- infiltration of the tumors by factor XIIIa + (F-XIIIa+), Mac 387+, CD68+, and LN3+ macrophages and dendrocytes (9060595)
- coexpression of CD34 or F-VIII and F-XIIIa by tumor cells (9060595)

See also

- epithelioid hemangioendothelioma (EHE)

Open References

- Fujii T, Zen Y, Sato Y, Sasaki M, Enomae M, Minato H, Masuda S, Uehara T, Katsuyama T, Nakanuma Y. Podoplanin is a useful diagnostic marker for epithelioid hemangioendothelioma of the liver. Mod Pathol. 2008 Feb;21(2):125-30. PMID: 18084256 Free