giant cell myocarditis
Synopsis
giant cell myocarditis
multinucleated giant cells contain lysozyme (not myosin or creatine phosphokinase)
multinucleated giant cells are probably derived from macrophage, rather than myocyte precursors.
Etiology
Bartonella henselae myocarditis
autoimmune diseases (19%)
- discoid lupus erythematosis (#15100760#)
- autoimmune hepatitis (#15100760#)
Associations
ulcerative colitis
mitral valve replacement (#6724575#)
References
Giant cell myocarditis after mitral valve replacement: case report and studies of the nature of giant cells. Rabson AB, Schoen FJ, Warhol MJ, Mudge GH, Collins JJ Jr. Hum Pathol. 1984 Jun;15(6):585-7. PMID: #6724575#