plasmacytoma

WKP

PO

Digital case

 HPC:334 : Nodal plasmocytoma

Images

 solitary plasmacytoma

• https://twitter.com/WebPathology/status/735940036064075777

 mass of the upper lip & mobility of maxillary incisors

• https://twitter.com/bunn_belinda/status/744985348065767424

 duodenal plasmocytoma

• https://twitter.com/DraEosina/status/880806225306411009

Localization

 nodal plasmacytoma
 extranodall plasmacytoma

• duodenal plasmocytoma
  • https://twitter.com/DraEosina/status/880806225306411009

Types

 IgA plasmacytoma

Plasmacytomas expressing immunoglobulin A are rare and not well characterized. Nodal and extranodal plasmacytomas expressing immunoglobulin A are an indolent lymphoproliferative disorder with a low risk of clinical progression.

IgA plasmacytomas may represent a distinct form of extramedullary plasmacytoma characterized by younger age at presentation, frequent lymph node involvement, and low risk of progression to plasma cell myeloma. (20871216)

See also

 nodal plasmocytic infiltrate

References

 Nodal and extranodal plasmacytomas expressing immunoglobulin A: an indolent lymphoproliferative disorder with a low risk of clinical progression. Shao H, Xi L, Raffeld M, Pittaluga S, Dunleavy K, Wilson WH, Spector N, Milito C, Morais JC, Jaffe ES. Am J Surg Pathol. 2010 Oct;34(10):1425-35.PMID: 20871216

 Nappi O, Boscaino A, Wick MR. Extramedullary hematopoietic proliferations, extraosseous plasmacytomas, and ectopic splenic implants (splenosis). Semin Diagn Pathol. 2003 Nov;20(4):338-56. PMID: 14694984