Pathology of cell-extracellular matrix interaction
mutations of kindlin-1 in Kindler syndrome (kindlin-1 is a human homolog of the Caenorhabditis elegans protein UNC-112 a membrane-associated structural/signaling protein that has been implicated in linking the actin cytoskeleton to the extracellular matrix)
References
Ffrench-Constant C, Colognato H. Integrins: versatile integrators of extracellular signals. Trends Cell Biol. 2004 Dec;14(12):678-86. PMID: 15564044
