Home > C. Tissular pathology > calcifications

calcifications

Monday 15 November 2004

tissular calcification

Images

Tumoral Calcinosis

https://twitter.com/WebPathology/status/862838614673285120

calciphylaxis

https://twitter.com/Valdebran/status/719512822221119488

Wikimedia: calcifications in a benign breast tissue / mammary calcifications

psammoma

psammoma in meningioma
- https://twitter.com/Haneen_Maghrabi/status/733520867683008512
- https://twitter.com/FotiosDaglis/status/715853862712778753

psammoma in papilary thyroid carcinoma (PTC)
- https://twitter.com/aakasharmand/status/847492220617805824

Digital slides

JRC:6443 : Metastatic pulmonary calcification.

Definition: Pathologic calcification is the abnormal tissue deposition of calcium salts, together with smaller amounts of iron, magnesium, and other mineral salts.

Types

tissular calcifications
post-necrotic calcifications
metastatic calcifications
tumoral calcifications

psammoma bodies / psammomas

in atherosclerotic plaque

Image: https://twitter.com/BeynonMD/status/718292728862400512

calciphylaxis

https://twitter.com/Valdebran/status/719512822221119488

Pathology

There are two forms of pathologic calcification. When the calcium deposition occurs locally in dying tissues, the phenomenon is known as post-necrotic calcifications (dystrophic calcification); it occurs despite normal serum levels of calcium and in the absence of derangements in calcium metabolism.

In contrast, the deposition of calcium salts in otherwise normal tissues is known as metastatic calcification, and it almost always results from hypercalcemia secondary to some disturbance in calcium metabolism.

Etiology

calcium metabolism anomalies
granulomatous processes