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cytoplasmic inclusions

Tuesday 24 August 2004

Types

- polyglucosan bodies (polyglucosan inclusions)

  • Lafora bodies
  • Lafora body-like inclusions
  • glycogen storage disease type IV (GSD4)
  • adult polyglucosan body disease (APBD)

- nigral inclusions

  • Lewy bodies
  • pale bodies

- intermediate filament inclusion bodies

  • Mallory bodies
  • tumoral juxta-nuclear inclusions

- spironolactone bodies in aldosterone secreting adrenal cortical adenoma

According to cell types

- hepatocytic cytoplasmic inclusions

  • Mallory bodies
  • ground-glass inclusions
  • Lafora bodies
  • Lafora-like bodies

- neuronal cytoplasmic inclusions
- oligodebdroglial cytoplasmic inclusions

  • alpha-synuclein-positive cytoplasmic oligodendroglial inclusions

Examples

- rhabdoid inclusions in clear cell renal cell carcinoma / clear cell RCC