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pulmonary granulomatosis with polyangiitis
Thursday 12 August 2004
pulmonary Wegener granulomatosis; GPA
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Wegener’s Granulomatosis in lung with vasculitis
Synopsis
- pulmonary arteritis
- pulmonary venulitis
- pulmonary capillaritis
- pulmonary acute vasculitis (acute mural inflammation)
- pulmonary chronic vasculitis (chronic mural inflammation)
- pulmonary granulomatous vasculitis (granulomatous mural inflammation)
- pulmonary vascular fibrinoid necrosis
- pulmonary endotheliolitis (pulmonary endothelitis)
pulmonary parenchymal lesions
- pulmonary parenchymal necrosis
- geographic necrosis
- geographic necrotizing granuloma with palisading of histiocytes
- neutrophilic microabscesses surrounded by granulomatous inflammation
- necrotizing granuloma
- granulomatous inflammation
- palissading granuloma (palissading histiocytes)
- scattered giant cells
- interstitial fibrosis
- scattered giant cells
- poorly formed granulomas
- sarcoid-like granulomas (rare)
- vasculitis
- granulomatous vasculitis
- vascular fibrinoid necrosis
- arteritis with fibrinoid necrosis
- arteriolitis
- capillaritis
- venulitis
- nodular interstitial fibrosis
- endogenous lipoid pneumonia
- alveolar hemorrhage
- organizing intraluminal fibrosis
- lymphocytic infiltrates
- eosinophilic infiltrates
- xanthogranulomatous lesions
- alveolar macrophage accumulation
bronchial lesions / bronchiolar lesions
- chronic bronchiolitis
- acute bronchiolitis
- acute bronchopneumonia
- bronchiolitis obliterans
- BOOP histologic pattern
- broncocentric granulomatosis
- follicular bronchiolitis
- bronchial stenosis
granulomatous tuberculoid inflammation
palisading microgranuloma
interstitial fibrosis
cicatricial vascular fibrosis
focal bronchiolitis obliterans
bronchocentric granulomatous inflammation
Differential diagnosis
lymphomatoid granulomatosis (diffuse large B-cell lymphoma, DLBCL)
Churg-Strauss disease
sarcoidosis
necrotizing sarcoid granulomatosis
rheumatoid nodules
bronchocentric granulomatosis
granulomatous infections
diffuse pulmonary hemorrhage syndromes
See also
granulomatosis with polyangiitis
diseases
- dysimmune diseases
vasculitis
granulomatous diseases
