Home > A. Molecular pathology > PPARG
PPARG
MIM.601487
Monday 5 July 2004
PPAR-gamma
Pathology
PAX8-PPARG fusion gene
- PAX8-PPARG fusion gene in thyroid follicular tumors
PPARG germ-line mutations
- in autosomal dominant familial partial lipodystrophy (MIM.604367)
- in severe insulin resistance and type II diabetes (MIM.125853)
- overrepresentation of a 1347C-T polymorphism in the PPARG gene in american patients with glioblastoma (MIM.137800)
somatic mutation of PPARG
- in colorectal adenocarcinoma
See also
PPARs
References
Campbell IW. The Clinical Significance of PPAR Gamma Agonism. Curr Mol Med. 2005 May;5(3):349-63. PMID: 15892654
Zhang L, Chawla A. Role of PPARgamma in macrophage biology and atherosclerosis. Trends Endocrinol Metab. 2004 Dec;15(10):500-5. PMID: 15541649
Lee CH, Evans RM. Peroxisome proliferator-activated receptor-gamma in macrophage lipid homeostasis. Trends Endocrinol Metab. 2002 Oct;13(8):331-5. PMID: 12217489
