diagnosis of adnexal tumors

See also : adnexal tumors

Questions / Clues

 sebocytes ?
  ducts ? glands ? tubules ?
 basaloid cells ?
 palisading cells ?
 cellular spindled stroma ?

Differentiation ?

 sweat gland derived

• eccrine gland derived : cutaneous eccrine tumors
• apocrine gland derived : cutaneous apocrine tumors

 hair follicles : hair follicle tumors > pilar tumors
 sebaceous glands : cutaneous sebaceous tumors

Architectural pattern ?

 cystic adnexal tumors

• microcystic adnexal tumors / cutaneous microscytsic tumors

 basaloid adnexal tumors / cutaneous basaloid cell tumors
 squamoid adnexal tumors
 glandular adnexal tumors

Patterns in sweat gland tumors

  cystic adnexal tumors

• dermal cyst with double cuboidal lining or columnar lining : hidrocystoma
• cystic space and papillary projections : syringocystadenoma papilliferum

 microcystic adnexal tumors

• syringoma
• trichoadenoma

 basaloid adnexal tumors

• - blue basaloid proliferation in dermis : spiradenoma and cylindroma

 squamoid adnexal tumors

• solid pink or clear or squamoid proliferation in epidermis and/or dermis +/- cystic change : acrospiroma

 tadpoles / Paisley tie syringoma

 dermal nodule with variable mixture of cords / chains / tubules and chondromyxoid stroma mixed tumor : chondroid syringoma

Diagnosis (examples)

 papillary projection in adnexal tumors

• hidradenoma papilliferum
• syringocystadenoma papilliferum

 glandular cavities

• hidradenoma papilliferum
• syringocystadenoma papilliferum

 double epithelial layers with basal myoepithelial cells

• hidradenoma papilliferum
• syringocystadenoma papilliferum

See also

 cutaneous tumors

• cutaneous adnexal tumors

 cutaneous appendages

Open references

 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860623/
 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1860616/