fibroblastic tumors

Classification

 benign fibroblastic tumors

• ischemic fasciitis
• nodular fasciitis
• fibrous hamartoma
• desmoplastic fibroblastoma
• mammary-type myofibroblastoma
• angiomyofibroblastoma
• cellular angiofibroma
• nuchal-type fibroma
• Gardner fibroma
• calcifying fibrous tumour
• giant cell angiofibroma

 intermediate fibroblastic tumors (fibrosarcomas )

• dermatofibrosarcoma protuberans (CD34+)
• giant cell fibroblastoma
• lipofibromatosis
• desmoid fibromatosis
• low-grade myofibroblastic sarcoma
• myxoinflammatory fibroblastic sarcoma

 malignant fibroblastic tumors (fibrosarcomas )

• congenital fibrosarcoma
• adult-type fibrosarcoma ( classic fibrosarcoma )
• low-grade fibromyxoid sarcoma (LGFMS)
• sclerosing epithelioid fibrosarcoma
• myxofibrosarcoma
• myofibrosarcoma
• inflammatory myxohyaline/myxoinflammatory fibroblastic sarcoma
• low-grade myofibroblastic sarcoma
• myxoinflammatory fibroblastic sarcoma
• low-grade fibromyxoid sarcoma
• sclerosing epithelioid fibrosarcoma

Diagnosis of fibroblastic tumors

 assess fibroblastic tumors

• can be CD34+

 mitotic count
 Ki67
 negative IHC : S100, desmin
 type of collagen associated

• desmoid-type collagen : desmoid fibromatosis

 paranuclear inclusion > digital fibromatosis / inclusion fibromatosis

See also

 fusiform cell tumors

• fibrous tumors
• myofibroblastic tumors
  • infantile myofibromatosis