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neonatal hepatic failure

Wednesday 19 May 2004

Etiology

- neonatal ischemic liver failure
- inherited metabolic diseases

  • tyrosinemia type 1
  • oxydative phosphorylation diseases
  • urea cycle diseases
  • galactosemia
  • fatty acid oxidation diseases
  • hereditary fructose intolerance
  • bile salts anomalies
  • congenital disorder of glycosylation syndrome (CDG syndrome)
  • Niemann-Pick type C disease

- infectious neonatal liver failure

  • Enterovirus
  • Herpes simplex virus infection (HSV1 and HSV2)
  • Hepatitis B virus infection (HBV)
  • Human herpes virus 6 (HHV6)
  • Other viruses
  • neonatal bacterial infections

- miscellaneous

  • neonatal haemochromatosis
  • hemophagocytic lymphohistiocytosis

- hepatic cellular infiltration

  • leukemias
  • neonatal tumors
    • neuroblastoma

- drugs
- autoimmune hepatitis
- hypocortisolism
- neonatal hypoxia
- neonatal ischemia

Associations

- neonatal hemochromatosis

See also

- acute liver failure
- neonatal liver diseases
- neonatal hepatitis

  • neonatal fulminant hepatitis

- neonatal massive hepatic necrosis
- acute liver failure
- neonatal hepatic diseases (neonatal liver diseases)

References

- Neonatal liver failure: aetiologies and management—state of the art. Shanmugam NP, Bansal S, Greenough A, Verma A, Dhawan A. Eur J Pediatr. 2011 May;170(5):573-81. PMID: 20886352

- Neonatal liver failure: a genetic and metabolic perspective. Saenz MS, Van Hove J, Scharer G. Curr Opin Pediatr. 2010 Apr;22(2):241-5. PMID: 20090522

- Neonatal liver failure. McClean P, Davison SM. Semin Neonatol. 2003 Oct;8(5):393-401. PMID: 15001127

- Neonatal liver failure. Shneider BL. Curr Opin Pediatr. 1996 Oct;8(5):495-501. PMID: 8946131