Home > A. Molecular pathology > factor-H
factor-H
Tuesday 4 May 2004
Pathology
factor-H mutations in 15-30% of patients with atypical hemolytic uremic syndrome (HUS)
Features
CD46 mutations in atypical hemolytic uremic syndrome (HUS)
References
Goodship TH, Liszewski MK, Kemp EJ, Richards A, Atkinson JP. Mutations in CD46, a complement regulatory protein, predispose to atypical HUS. Trends Mol Med. 2004 May 1;10(5):226-231. PMID: 15121049
