Home > E. Pathology by systems > Skin > epidermolytic hyperkeratosis
epidermolytic hyperkeratosis
MIM.113800
Thursday 18 March 2004
bullous ichthyosis; bullous congenital ichthyosiform erythroderma
Images
7 day old baby. erythrodermia and bullous lesions.
Etiology
germ-line mutations
Differential diagnosis
epidermolytic acanthoma
warts (especially of the palmoplantar type )
epidermal nevi
bullous ichthyosiform erythroderma
ichthyosis hystrix
keratoderma palmaris et plantaris
nevus unis lateris
in tumors such as:
- infundibular cysts
- seborrheic keratosis
- actinic keratosis
See also
keratins (KRTs )
keratinopathies
References
Yang JM, Nam K, Kim SW, Jung SY, Min HG, Yeo UC, Park KB, Lee JH, Suhr KB, Park JK, Lee ES. Arginine in the beginning of the 1A rod domain of the keratin-10 gene is the hot spot for the mutation in epidermolytic hyperkeratosis. J Dermatol Sci. 1999 Feb;19(2):126-33. PMID: 10098704
Fuchs E, Coulombe P, Cheng J, Chan YM, Hutton E, Syder A, Degenstein L, Yu QC, Letai A, Vassar R. Genetic bases of epidermolysis bullosa simplex and epidermolytic hyperkeratosis. J Invest Dermatol. 1994 Nov;103(5 Suppl):25S-30S. PMID: 7525738
