Home > E. Pathology by systems > Digestive system > Liver and pancreatobiliary system > Liver > macrotrabecular massive hepatocellular carcinoma
macrotrabecular massive hepatocellular carcinoma
Monday 26 September 2022
macrotrabecular-massive HCC
| PO |
Definition : Subtype of hepatocellular carcinoma with macrotrabecular pattern (≥ 6 - 10 cells thick). Macrotrabecular pattern must represent more than 50% of the tumor.
Images
https://twitter.com/emma_furth/status/1574870532452864000
Synopsis
hepatocellular carcinoma
> 50% growth of macrotrabecular pattern (≥ 6 - 10 cells thick)
Trabeculae observed in cross sections are bordered by a complete rim of CD34 positive endothelial cells in more than half of the tumor area (vessels encapsulating tumor clusters (VETC))
Associated with micro and macrovascular invasion (> 60%)
Associated with higher tumor cell grade and presence of anaplastic tumor cells
See also
hepatocellular carcinoma ( HCC )
