Home > B. Cellular pathology > necrotic cells
necrotic cells
Sunday 10 April 2022
Morphology
Necrotic cells show increased eosinophilia attributable in part to loss of the normal basophilia imparted by the RNA in the cytoplasm and in part to the increased binding of eosin to denatured intracytoplasmic proteins.
The necrotic cells may have a more glassy homogeneous appearance than that of normal cells, mainly as a result of the loss of glycogen particles. When enzymes have digested the cytoplasmic organelles, the cytoplasm becomes vacuolated and appears moth-eaten. Finally, calcification of the dead cells may occur.
Examples
necrotic keratinocytes
necrotic hepatocytes
See also
necrosis
- tissular necrosis
- cellular necrosis
