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glutamine synthetase

Monday 2 August 2021

GLUL

WKP PO

Definition : Glutamine synthetase (GS) (EC 6.3.1.2)[3] is an enzyme that plays an essential role in the metabolism of nitrogen by catalyzing the condensation of glutamate and ammonia to form glutamine:

Glutamate + ATP + NH3 → Glutamine + ADP + phosphate

Diagnostic use

- hepatocellular carcinoma (HCC)

See also

- IHC markers