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vesiculobullous and acantholytic reaction pattern
Thursday 11 February 2021
vesiculobullous and acantholytic reaction patterns
|PO|
spongiosis: accumulation of extracellular fluid within epidermis with resultant separation of keratinocytes
- eczematous dermatitis
- allergic contact dermatitis
- miliaria
acantholysis: loss of appropriate keratinocyte cell-cell contact
- pemphigus
- transient acantholytic dermatosis
- Hailey-Hailey
- Darier disease
- Grover disease / transient acantholytic dermatosis
- irritant dermatitis
reticular degeneration: ballooning degeneration with secondary rupture and death of the keratinocytes
- viral infections
- eczematous dermatitis
cytolysis : disruption of keratinocytes due to friction or heat
- EB simplex
- epidermolytic hyperkeratosis
- friction blister
basement membrane zone disruption or destruction from primary structural deficiencies, humoral and cellular immunologic damage
- bullous pemphigoid
- cicatricial pemphigoid
- linear IgA
- dermatitis herpetiformis
- epidermolysis bullosa acquisita
- junctional epidermolysis bullosa
- epidermolysis bullosa dystrophica
See also
cutaneous lesional patterns