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peripheral lobular fibrosis

Friday 13 November 2020

Etiology

- abnormal senescence

  • telomerase mutations / familial IPF
  • short telomeres
  • MUC5B

See also

- pulmonary fibrosis

Open references

- Pathogenesis of idiopathic pulmonary fibrosis: review of recent findings.2014. PMID: 25165568

- Genetic studies provide clues on the pathogenesis of idiopathic pulmonary fibrosis. 2013. PMID: 23268535

- The epithelium in idiopathic pulmonary fibrosis: breaking the barrier. 2014. PMID: 24454287

- Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin. 2016. PMID: 26968767

Paywall references

- Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis. PMID: 31034279

- MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease. PMID: 30345907

- Reduced mucociliary clearance in old mice is associated with a decrease in Muc5b mucin. PMID: 26968767