Home > E. Pathology by systems > Reproductive system > Female genital system > complete hydatiform mole
complete hydatiform mole
Monday 15 July 2019
complete mole
Examples
complete hydatiform mole
- https://twitter.com/luishcruzc/status/738155933801418752
- https://twitter.com/KUSAURAP/status/778827207976230916
Synopsis
large villi distended with abundant stromal fluid and formation of a cistern.
Strands of fibrillar material are seen within and around the cistern.
Trophoblastic proliferation is seen.
nodular trophoblastic hyperplasia (seen as eosinophilic nests and clusters).
Haphazard circumferential proliferation of cytotrophoblast and syncytiotrophoblast around individual villi in this image.
Some of the nuclei show considerable atypia.
club-shaped villi in a complete mole.
Between 5% to 15% of patients with complete moles may develop persistent gestational trophoblastic neoplasia requiring chemotherapy.
Serial determinations of serum hCG levels are helpful in optimizing treatment.
See also
partial hydatiform mole
