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nasal granulomatosis with polyangiitis

Wednesday 7 January 2004

nasal Wegener granulomatosis; nasal GPA




- vascular lesions

- extravascular lesions

  • palisading granuloma in all cases
  • microabscess in 91%
  • diffuse granulomatous tissues in 82%
  • Palisading microgranuloma (82%) was more frequent than palisading macrogranuloma (45%)


- Matsubara O, Yoshimura N, Doi Y, Tamura A, Mark EJ. Nasal biopsy in the early diagnosis of Wegener’s (pathergic) granulomatosis. Significance of palisading granuloma and leukocytoclastic vasculitis. Virchows Arch. 1996 Apr;428(1):13-9. PMID: 8646364